Background:

FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14kd or 18kd.

Applications:

WB

Name of antibody:

FXN

Immunogen:

Fusion protein of human FXN

Full name:

frataxin

Synonyms：

CyaY; FA; FARR; FRDA; MGC57199; X25

SwissProt:

Q16595

WB Predicted band size:

23 kDa

WB Positive control:

MDA-MB-453s cells

WB Recommended dilution:

500-2000