Background:

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.

Applications:

ELISA, IHC

Name of antibody:

FZD2

Immunogen:

Synthetic peptide of human FZD2

Full name:

led family receptor 2

Synonyms：

Fz2; fz-2; fzE2; hFz2

SwissProt:

Q14332

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human renal cancer

IHC Recommend dilution:

25-100