Background:

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

VPS45

Immunogen:

Fusion protein of human VPS45

Full name:

vacuolar protein sorting 45 homolog

Synonyms:

H1; SCN5; VSP45; VPS45A; VPS45B; VPS54A; VSP45A; H1VPS45

SwissProt:

Q9NRW7

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

30-150