Background:

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Applications:

WB

Name of antibody:

WEE1(Phospho-Ser642)

Immunogen:

Peptide sequence around phosphorylation site of Serine 642(S-V-S(p)-L-T) derived from Human WEE1.

Full name:

WEE1 G2 checkpoint kinase

Synonyms：

WEE1A; WEE1hu

SwissProt:

P30291

WB Predicted band size:

72 kDa

WB Positive control:

293 cells lysates treated with etoposide

WB Recommended dilution:

500-1000