Background:

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

Applications:

WB

Name of antibody:

OAT

Immunogen:

Synthesized peptide derived from Internal of human OAT.

Full name:

ornithine aminotransferase

Synonyms：

OKT; GACR; HOGA; OATASE

SwissProt:

P04181

WB Predicted band size:

49 kDa

WB Positive control:

K562 and COLO205 lysates

WB Recommended dilution:

500-3000