Background:

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

ELISA, IHC

Name of antibody:

SGK1

Immunogen:

Synthetic peptide of human SGK1

Full name:

serum/glucocorticoid regulated kinase 1

Synonyms：

SGK

SwissProt:

O00141

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

25-100