Background:

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Applications:

ELISA, IHC

Name of antibody:

MRC1

Immunogen:

Synthetic peptide of human MRC1

Full name:

mannose receptor, C type 1

Synonyms：

MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1

SwissProt:

P22897

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

15-50