Background:

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

Applications:

WB, IHC

Name of antibody:

PEA15(Phospho-Ser104)

Immunogen:

Peptide sequence around phosphorylation site of Serine 104(I-P-S(p)-A-K) derived from Human PEA-15.

Full name:

phosphoprotein enriched in astrocytes 15

Synonyms：

PED; MAT1; HMAT1; MAT1H; PEA-15; HUMMAT1H

SwissProt:

Q15121

IHC positive control:

Human heart tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

15 kDa

WB Positive control:

COS cells lysates treated with TNF

WB Recommended dilution:

500-1000