Background:

This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.

Applications:

IHC

Name of antibody:

PHLDA2

Immunogen:

Synthesized peptide derived from internal of human PHLA2.

Full name:

pleckstrin homology-like domain, family A, member 2

Synonyms：

IPL; BRW1C; BWR1C; HLDA2; TSSC3

SwissProt:

Q53GA4

IHC positive control:

Human placenta tissue

IHC Recommend dilution:

50-100