Background:

The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation.

Applications:

ELISA, WB, IHC

Name of antibody:

TRAFD1

Immunogen:

Fusion protein of human TRAFD1

Full name:

TRAF-type zinc finger domain containing 1

Synonyms：

FLN29

SwissProt:

O14545

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

65 kDa

WB Positive control:

Mouse spleen tissue

WB Recommended dilution:

200-1000