Background:

This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Applications:

ELISA, WB, IHC

Name of antibody:

TMPRSS11D

Immunogen:

Fusion protein of human TMPRSS11D

Full name:

transmembrane serine protease 11D

Synonyms:

HAT

SwissProt:

O60235

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and Human liver cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

46 kDa

WB Positive control:

Rat liver tissue lysate

WB Recommended dilution:

1000-5000