Background:

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

Applications:

WB

Name of antibody:

TAOK3

Immunogen:

Synthesized peptide derived from internal of human TAOK3.

Full name:

TAO kinase 3

Synonyms：

DPK; JIK; MAP3K18

SwissProt:

Q9H2K8

WB Predicted band size:

105 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000