Background:

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

MSLN

Immunogen:

Fusion protein of human MSLN

Full name:

mesothelin

Synonyms：

MPF; SMRP

SwissProt:

Q13421

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human cervical cancer and Human lung cancer

IHC Recommend dilution:

50-200